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Guanfacine Making Him Sad?

We are on vacation at the beach. Ewen has been taking 1/4 guanfacine at 8am and 4pm for the past couple of days and it has already greatly reduced his tics. But today I don't think he smiled once. He has been craving sugar, begging for sweets which he does when he is depressed. He is dissatisfied with every activity and is on his iPod all the time.

I don't know if the change is because of going down to 4 ml's of Prozac but I think that the guanfacine, even with this tiny dose, is making him depressed, even with the Prozac.

So we decided that tomorrow we would not give him the guanfacine and see how he feels.

Our options are:

1. stop the guanfacine
2. increase the prozac to 5ml's again and keep taking the guanfacine
3. just take the guanfacine at night, around 7pm so that his tics aren't as bad when he falls asleep. He said he likes how he is calmer and less twitch on the guanfacine. But he doesn't like that he feels "blegh". He is not happy on vacation and that makes me sad. He has no joy in him right now.

I'm thinking that we should put up the prozac to 5 ml's which is when he was finally joyful again and see if the guanfacine helps with the tics.

Before the guanfacine he was grumpy too when we went to my friend's birthday dinner. So I'm not sure what to do. I hate raising his meds, horrible stuff. But I also want him to be able to enjoy his life again. This is heartbreaking.

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